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8.5.5.1 Complexity and cost of manufacturing Many advanced formulations, particularly those involving nanotechnology (liposomes, polymeric nanoparticles, SMEDDS), require complex manufacturing processes, specialized equipment, and stringent quality control

Saunders Elsevier Publishers, Philadelphia, Pa, 2006 13

Both sucrose and aspartame dosages markedly elevated MAO, AChE, and BChE activities, increased TBARS and ROS levels, and suppressed antioxidant enzyme activities in the hippocampus
