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Raj GM, Raveendran R (2019) Introduction to basics of pharmacology and toxicology: volume 1: general and molecular pharmacology: Principles of drug action
Additionally, patients with inflammatory bowel disease, severe gastroesophageal reflux disease, or other significant gastrointestinal disorders should be monitored closely if treatment is initiated, as the gastrointestinal effects of semaglutide may worsen their underlying condition

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These are signals worth discussing, not a diagnosis
