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For a non-dietary cause, maintenance is usually one injection every two to three months for life

Using surface plasmon resonance (SPR) binding and fluorescence polarization (FP) competition assays, we obtained a base compound, 1907, with enhanced binding capabilities compared to native LD2

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In 2011, 70% of the procedures involved chondroplasty (smoothing the defect by removing loose strands of cartilage), 28% involved microfracture or subchondral drilling (techniques used to release marrow elements), and only 2% involved the use of advanced cartilage restoration techniques (osteochondral autograft transfer, ACI)