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Excessive ROS can cause oxidative stress, resulting in DNA damage, protein misfolding, organelle lesion, and neuronal synaptic dysfunction (32)

"All committee members underwent the same ethics review and vetting process required of all FDA advisory committee members

Beyond recapitulating established pathways, we dedicate considerable attention to translational implications, systematically evaluating potential therapeutic avenues such as anti-inflammatory modulation, oxidative stress mitigation, and lung microbiota remodeling

In AD, chemokines serve as critical mediators bridging innate and adaptive immunity (Sun et al., 2021), as part of the broader mechanisms illustrated in Figure 4