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[DOI] [PubMed] [Google Scholar] 100.Guo H.L., Jing X., Sun J.Y

Lysine provides the carbon chain of carnitine, and methionine provides methyl groups

Down regulated pathways included protein ubiquitination, glucose metabolism, mitotic metaphase and anaphase, ribosomal quality control, and roundabout (ROBO) signaling pathways in APOE4 female mice ( Figure 1E )

Our results indicated that all the fourteen selected acyl-carnitines with FDR q 1.0 (i.e., C2, C8, C10, C10:1, C10:2, C12, C12:1, C14:1, C14:1-OH, C14:2, C14:2-OH, C16:2, C16:2-OH, and C18) were lower in posttreatment patients after controlling age, sex, BMI, smoking, and drinking (Tables 3 and 4)