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Curcumin also shows binding potential to matrix metalloproteinase 3 (MMP-3), a protease whose expression and activity are elevated in chronic inflammatory diseases, including RA (33)

doi: 10.1016/0378-1119(94)00448-2

Synbiotic supplementation may thereby change the makeup and roles of the gut microbiota and lower systemic inflammation and SLE disease activity (Widhani et al

This can be particularly beneficial for patients with significant deficiencies or those needing intensive support
