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Total cholesterol levels fell by approximately 30%
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Intranasal delivery of DSIP is straightforward

However, for specific injuries (like a damaged nerve in the leg), many researchers prefer administering it near the site to maximize local concentration, though the science supports its efficacy via systemic absorption as well

A large cohort study found that the hazard ratio for VTE in transgender women receiving oral estrogen was 2.7 (95% CI, 1.2-6.1) compared to cisgender women, although this increased risk was not observed with transdermal estrogen
