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Participants consumed two chewable tablets twice daily (at breakfast and after school), with each tablet containing 100 mg of L-theanine (total 400 mg daily Suntheanine, Taiyo Kagaku, Yokkaichi, Japan) or identical tasting chewable placebo for six weeks

A few isolated observations also suggest that L-carnitine may be useful in patients with coma or in preventing hepatic dysfunction after acute VPA overdose

The resultant reduction in cAMP leads to decreased cAMP-dependent protein kinase (PKA) activity and diminished phosphorylation of pyruvate kinase and phosphofructokinase-2, PFK-2