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Therefore, these results suggested that 1919 GBM cells overexpressing PSPH and PSPH V116I presented a more aggressive phenotype with increased synthesis of nucleotides and utilization of NAD and NADP, which leads to superior mitochondrial function in support of fueling the pool of ATP, nucleotides, and antioxidants
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Recent advances in immunotherapy approaches against MPNST growth have highlighted how these cancers might evade immune recognition and hijack immunological functions (e.g
