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It is also possible that in active acromegaly, chronic exposure to elevated IGF-I levels resets IGF-IR responsiveness via the induction of IGF-IR resistance (70), as it has been demonstrated that prolonged stimulation with IGF-I induces functional IGF-IR resistance in vitro through the negative feedback loop (72)
doi: 10.1165/rcmb.2009-0169TR
Additional research has demonstrated the efficacy of BPC-157 in protecting against and healing gastric ulcers in animal models, highlighting its potential therapeutic applications in gastrointestinal disorders
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Memantine in Alzheimer's Disease
