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what increases in g6pd deficiency usmle oxidized glutathione vs reduced ๐งฌ ๐๐ฒ๐ฃ๐ ๐๐ฒ๐ณ๐ถ๐ฐ๐ถ๐ฒ๐ป๐ฐ๐ โ ๐๐ถ๐ด๐ต ๐ฌ๐ถ๐ฒ๐น๐ฑ ๐ ๐ป๐ฒ๐บ๐ผ๐ป๐ถ๐ฐ๐ โก ๐๐ฎ๐๐ ๐ข๐๐ฒ๐ฟ๐๐ถ๐ฒ๐ ๐งฌ X-linked recessive โ โ NADPH โ RBCs can't handle oxidative stress ๐งซ NADPH keeps active โ protects RBCs ๐ Triggers ( G6PD deficiency and NADPH importance
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Lopez Guerra JL, Gomez DR, Lin SH, Levy LB, Zhuang Y, Komaki R, Jaen J, Vaporciyan AA, Swisher SG, Cox JD, Liao Z, Rice DC
Modulation of MAPK and NF-B signaling pathways by antioxidant therapy in skeletal muscle of heart failure rats

M.KawasakiM.SteckoT.RyanT

In gastric cancer cells, silencing SIRT1 leads to upregulation of p53 and downregulation of SLC7A11, indicating that SIRT1 suppression promotes ferroptosis
