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Researchers considering extended protocols should be aware that this safety gap exists and should monitor for unexpected effects in tissues where NNMT has normal physiological functions

Most researchers report initial changes between two and three months, with more substantial improvements visible at four to six months

The most common culprits: Prednisone / prednisolone T38.0X5A (adverse effect, glucocorticoids) Dexamethasone T38.0X5A Methylprednisolone T38.0X5A Antipsychotics (olanzapine, clozapine) T43.595A or T43.505A Tacrolimus (transplant drug) T45.1X5A Step 2: Sequence the T-code first, then E09.x, then the complication code, then Z79.4 if insulin was started

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