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CRP binds and aggregates oxidized low-density lipoprotein (ox-LDL) and enhances macrophage oxLDL uptake, promoting mitogen-activated protein kinase activation (171) required for foam cell formation (172)

In neuroblastoma (N2a), curcumin induced NEP promoter demethylation and restored its inhibition of the Akt/NF-B pathway (Deng et al., 2014)

All quantified proteins with non-missing values were included in the ranking

Zollner C, Mousa SA, Fischer O, Rittner HL, Shaqura M, Brack A, Shakibaei M, Binder W, Urban F, Stein C, Schafer M: Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain