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This challenge spurred the development of not only degradation-resistant GLP1R agonists but also DPP-4 inhibitors, which prolong the half-life of endogenous GLP-1 by blocking the enzyme (Ling et al., 2019)

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10.1016/S0920-1211(02)00073-6 122 LscherW.SchmidtD

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Caspase-3 targets pro-interleukin-1 (IL-1) to restrict inflammation

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