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Important things to consider for the rate of administration include: Watching the patients vital signs Changing the rate based on how the patient reacts Not giving it too fast to prevent bad reactions Emergency Protocols for Severe Deficiency For severe Vitamin B12 deficiency with neurological symptoms or severe anemia, emergency steps are needed

Gently aspirate by pulling back slightly on the plunger to check for blood: If blood appears , stop, withdraw, and restart in a new spot

Assuming an arbitrary threshold of 99% of the fitted saturated level, it corresponded to B 12 = 488 pg/mL (Figure 2)

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