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Tirzepatide has been shown in clinical trials to significantly reduce visceral fatthe harmful fat stored around organs in the abdomen, which contributes to metabolic diseases like type 2 diabetes and cardiovascular disease, while also being influenced by human growth hormone levels

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CD38 ligation plays a direct role in the induction of IL-1beta, IL-6, and IL-10 secretion in resting human monocytes

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doi: 10.1038/s41389-018-0064-4 17 CantoniGL

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