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Acetaldehyde can change the structure of mitochondria and cause its dysfunction, including damage to the respiratory chain, resulting in a decrease in ATP, the production of ROS, and a decrease in the activity of acetaldehyde dehydrogenase (Seitz et al., 2018)

(2019) observed that monocytes expressing Ly6Chi (with phagocytic and pro-inflammatory properties) secrete pro-inflammatory cytokines that attract more neutrophils and monocytes to the site of injury

This link was explained that chronic inflammation within the prostate due to the exposure of microbial agents stimulates the production of ROS and inflammatory cytokines leading to carcinogenesis (Coussens and Werb, 2002

doi: 10.1080/00016480410023038