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While prompt and efficient healing of skin wounds is essential to maintaining the vital barrier function of the skin, a pathological wound healing response can result in abnormal extracellular matrix (ECM) deposition and diminished degradation, ultimately leading to scarring and fibrosis (Figure 2)

Managing Side Effects in Research Settings Strategies that have proven effective in clinical trials for managing cagrilintide-related side effects include: Slower titration schedules Extending time between dose increases Meal timing adjustments Taking doses after meals rather than before Hydration optimization Maintaining adequate fluid intake Dietary modifications Smaller, more frequent meals

doi:10.1093/aje/kwg166

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