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This pathological synaptic loss significantly affects gray matter volume in critical brain regions, such as the prefrontal cortex, which is essential for higher cognitive functions (38,44)

To address the major differences in glutaredoxin activities, we previously suggested two nonexclusive working models for glutaredoxin catalysis termed glutathione scaffold and glutathione activator model

Apoptosis is a form of programmed cell death characterized by cell and nuclear shrinkage while maintaining membrane integrity (Li et al., 2020)

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