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doi: 10.1016/j.bbi.2018.11.002 239 LaidlawBJCysterJG

Enzymatic Mechanisms for Catalysis of Enolization: Ketosteroid Isomerase

While the majority of ALS cases (9095%) are sporadic (sALS), among familial ALS cases 510% involve the inheritance of mutations in the TARDBP gene and the remaining (9095%) are due to mutations in other genes such as: C9ORF72, SOD1, FUS , and NEK1 etc

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