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Description
To shed light on whether EBV infection might be a causative agent after invading the CNS following systemic infection, studies were done looking for evidence of virus in the MS brain

This was shown in HEK 293 cells, known to have voltage-gated K + [272,273], Na + [274], and Ca 2+ [275] channels, and with different local anesthetics applications (i.e., bupivacaine [89], lidocaine [60], tetracaine [276], and oxibuprocaine [276])

Long-term safety appears favorable when used under medical supervision with appropriate monitoring

10.1074/jbc.TM117.000180
