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Neuroinflammation 9, 115 (2012)

The principal eosinophil peroxidase product, HOSCN, is a uniquely potent phagocyte oxidant inducer of endothelial cell tissue factor activity: a potential mechanism for thrombosis in eosinophilic inflammatory states

The mechanism involves RMRP binding to WT1 associated protein (WTAP) in astrocytes, reducing the expression of WTAP and the m6A modification of p53 mRNA, ultimately fostering a supportive microenvironment for neuronal axonal regeneration

Furthermore, curcumin tends to accumulate in hydrophobic regions after application, for example, cell membranes, where it acts as a hydrophobic degrader (antioxidant) to scavenge various reactive oxygen species (ROS) and is better than vitamin E in inhibiting oxidative stress [120]