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Crisafulli S, Sultana J, Fontana A, et al

528,529,530,531,532,533,534,535,536,537 Moreover, TCM have shown activation of PI3K/Akt, 522,523,524,525,526 NF-B, 538,539,540 HIF-1, 541 and Notch signaling pathways 542 during organ injury treatment, indicating their potential to alleviate I/R injury by targeting multiple signaling pathways

However, as with most things in biology, principles are not the same as rules, biological individuality sometimes confirms this

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