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Description
Other signs of vitamin B12 deficiency in diabetics include a sore tongue, yellowish skin, pale complexion, breathlessness, irregular heartbeat, anemia, loss of balance and a tingling sensation in the hands and feet
Other than designing peptides that competitively bind to the CatB/L protease, peptides that inhibit endosomal acidification can also be used to inhibit the activity of CatB/L and other host cell proteases that is pH-dependent [93, 94]
Appetite effects are not strongly characterized in either direction in the current evidence base
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