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These results come from an animal model and cannot be directly transferred to humans

However, this approach does not account for situations in which the neutralization assay had neutralization titers below the LOD, therefore we also used a second method, in which we estimated this value by extracting the neutralization titers from the figures in each immunogenicity study (Supplementary Table 1) and computing the mean neutralization titer for vaccinated and convalescent individuals in each study using censoring regression (equation 1)