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Mutations in ASH1L disrupt the expression of the NTRK2 gene that encodes the TrkB receptor, leading to impaired neurite outgrowth and synaptic deficits associated with ASD [149]
Briefly, samples were prepared in 5% metaphosphoric acid to remove proteins
[] In rat models, NAC and deferoxamine prevent protein deterioration in the PFC and hippocampal regions
