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IGF-1 overexpressed mesenchymal stem cells can promote the migration, growth, and proliferation of bone marrow-derived mesenchymal stem cells by activating the AKT/SFRP2 signaling pathway, and inhibit cell apoptosis (125)
ESMO Open 6(6), 2021
Its important to note that GLP-2, a hormone involved in intestinal growth, is not targeted by either of these medications
However, in our study, oxidative stress-induced cell death was triggered by lipid peroxidation instead of the canonical mitochondrial ROS accumulation
