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Description
Lancet Gastroenterol

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[21] After the solution is deposited into muscle, cholecalciferol diffuses into the circulation bound to vitamin-D-binding protein and undergoes 25-hydroxylation in hepatocytes, yielding 25-hydroxyvitamin D, the principal circulating biomarker of status

The cytoplasmic calcium-activated calpain cleaves and activates caspase-12 in response to ER-released calcium (Tan et al., 2018)
