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We set out to validate these 6 proteins and 3 proteins with a high intensity that showed only a weak increase (C3, Fibrinogen, and SAP)

For in vivo experiments, compounds were dissolved in a 50:50 (v/v) ethanol/sesame oil mixture and topically applied daily to the dorsal skin of K14-Kitl mice for 2 weeks

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These clinical samples were used for transcriptome sequencing and immunostaining assays
