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Damaged melanocytes release danger-associated molecular patterns (DAMPs), including heat shock proteins (HSPs) and oxidized lipids, which activate innate immune responses and promote the recruitment of autoreactive T cells, mediated by the release of pro-inflammatory cytokines, including IL-15, IL-17, and IL-1beta [80,81]

However, the acetaldehyde concentration in serum was significantly lower in the GSH group compared to the placebo group at all time points, indicating that GSH treatment effectively reduced acetaldehyde, which is a direct cause of hangovers

Oxidative stress-mediated atherosclerosis: mechanisms and therapies

doi:10.1016/j.taap.2011.12.018 [7] Marques AC, Mariana M, Cairrao E