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Furthermore, nuclear factor erythroid 2-related factor 2 (Nrf2), a core regulator of oxidative stress responses, suppresses ferroptosis through promoting FTH1 transcription, which helps maintain iron balance and improve antioxidant capacity (Qian et al., 2024)

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Recently, new generations of more stable and potent GST-activated NO prodrugs have been developed (Liu et al., 2012

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