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doi: 10.1126/science.4001945
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas
In contrast, persistent increased OS might become toxic for functionality by targeting autophagic components and impairing the process at different steps (FIGURE 10)
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