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In a previous study, transcriptomic profiling of brain regions involved in the brains reward circuitry (prefrontal cortex, dorsal striatum, nucleus accumbens, basolateral amygdala, ventral hippocampus, and ventral tegmental area) revealed considerable changes in transcript expression during the cocaine self-administration, withdrawal, and relapse phases, with the greatest changes detected in the re-exposure phase 40
On basis of what have been done on herb-warfarin interactions, the current review aims at complementing the missing points from previous studies as summarized below: classification of clinical significance: life threaten, bleeding, INR change, and so forth
