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Numerous studies revealed that cancer is the results of oxidative DNA damage by ROS, in which hydroxylation of bases of DNA molecule take place followed by change in DNA structure

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PMID: 19884429 Ploumis, A., Ponnappan, R.K., Sarbello, J., Dvorak, M., Fehlings, M.G., Baron, E., Anand, N., Okonwko, D.O., Patel, A., Vaccaro A.R..: Thromboprophylaxis in traumatic and elective spinal surgery: Analysis of questionnaire response and current practice of spine trauma surgeons

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