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The formula used is: Fifty = (Top + Baseline)/2 and Y = Bottom + (TopBottom)/(1 + 10^((LogAbsoluteIC50X) * HillSlope + log((TopBottom)/(FiftyBottom)1))))

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They can bind to free fatty acid receptors (FFARs) on immune cells, while butyrate, as a HDAC inhibitor, can upregulate the expression of anti-inflammatory genes and induce microglial polarization toward an anti-inflammatory phenotype (Zhao et al., 2022

Kim and coworkers in 2017 observed decreased levels of - and -carotenes and lycopene in plasma, which decreased with the duration of PD
