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And let us renew our commitment to work with the oppressed and marginalized to stand between injustice and those whose lives are affected by it

Glutathione exists in reduced (active) and oxidized forms

FIGURE 4 GSTP1 Activity in GSH-Conjugation of AQ-QI and DEAQ-QI To investigate the intracellular GSTP1-mediated GSH-conjugation of AQ-QI or DEAQ-QI, AQ-SG, and DEAQ-SG formation were measured in total lysates directly after QI exposure

However, a dysregulated increase in the level of these free radicals, as seen in mitochondrial diseases, can result in oxidative damage by overwhelming the cellular antioxidant defence mechanism, of which glutathione is the principal component [4]
