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Currently, many researchers believe that SGLT2 inhibitors exert their cardioprotective effects by increasing ketone bodies

Ethical Approval This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by the author

The same shuttling system can also export excess acetylcarnitine out of the mitochondria to limit inhibition of pyruvate dehydrogenase and spare the pool of free CoA necessary for other molecules
