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Similarly, Cheung et al [56] demonstrated that miR-125b-5p expression is upregulated by glucose in an AMP-activated protein kinase (AMPK)-dependent manner and targets the transporter of lysosomal hydrolases, cation-dependent mannose-6-phosphate receptor (M6PR), and the mitochondrial fission regulator, mitochondrial fission process protein 1 (MTFP1), to regulate organelle dynamics and impair glucose-stimulated insulin secretion

Periyasamy P, Singh S, Oladapo A, Kannan M, Buch S

Depending on your skin objectives, a course of treatments may be suggested