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Clinical research has demonstrated the effectiveness of PD1/PDL1 inhibitors, such as pembrolizumab and nivolumab, in treating patients with brain metastases of NSCLC [208]
The 10 antibodies including IgG-A and IgG-B purified by the standard method irreversibly aggregated after the concentration step (Table 2 and Fig
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The C-terminal difference between the two variants makes GAC more specifically active, which may contribute to its greater susceptibility to overexpression in aggressive cancers (Redis et al., 2016)
