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Collectively, GLPs show strong therapeutic efficacy against retinal pathologies induced by ischemiareperfusion injury, acting via a multi-faceted pharmacological profile that includes antioxidant, anti-inflammatory, anti-apoptotic, anti-angiogenic, and gliosis-modulating activities
82 NiaHTLiuHSeanoGDattaMJonesDRahbariNet al
ViaCytes VC-02 product (phase 1/2, NCT03163511) demonstrated proof-of-concept for graft survival and C-peptide production in some patients, but inconsistent engraftment and fibrotic encapsulation have hampered insulin output [138]
