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N-aryl benzimidazole (NAB) compounds enhance Parkin activity, promote clearance of damaged mitochondria and reduce oxidative stress in PD
Activation of TRPV1 restored GPX4 levels, reduced lipid peroxidation, and improved cartilage integrity in both IL-1treated chondrocytes and OA mouse models (42)
The lipoic acid analogue CPI-613 was shown to selectively inhibit PDH activity and inhibit the growth of PDAC [315]
Acta Physiol (Oxf) 2008;194:283291
