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While numerous studies have emphasized its antioxidant, anti-inflammatory, and nephroprotective properties, there is insufficient consensus on the specific bioactive components responsible for these effects or their precise mechanisms of action

While immune and neuroinflammatory responses are protective against infection and injury, excessive activity in these pathways can damage normal tissues, leading to inflammatory injury of dopaminergic neurons and driving PD progression ( In MPTP-induced PD mouse models, astragaloside IV (AS-IV), the primary active component of Astragalus membranaceus (Fisch.), administered at doses of 1.5, 3, and 6 mg/kg for 10 days, demonstrated dose-dependent improvements in motor dysfunction

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Tsamesidis I., Reybier K., Marchetti G., Pau M.C., Virdis P., Fozza C., Nepveu F., Low P.S., Turrini F.M., Pantaleo A

Bio/Physico-chemical Assay Bio/Physico-chemical Assay Bio/Physico-chemical Assay Bio/Physico-chemical Assay All Endogenous Metabolite Isoforms More Biological Activity 13 C 5 is the 13 C-labeled L-Glutamine (HY-N0390)