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Specifically, five biomolecules, including four enzymesascorbate peroxidase, catalase, glutathione reductase and superoxide dismutase, as well as one reactive oxygen species (ROS)hydrogen peroxide, are known to perturb in RRS [6] -[8]

Journal of neurochemistry 2001, 76 (6), 17661773

The underlying biochemical lesion is a reduction in the activity of lipoprotein lipase, and the disorder is transmitted as an autosomal recessive gene
