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(2013) reported no significant variations in key pharmacokinetic parameterspeak time (Tmax), t1/2, and AUCbetween Day 1 and Day 7, suggesting stable pharmacokinetics with prolonged administration

With these introductory considerations in mind, I review findings from many different viruses with a particular focus on HIV and SARS-CoV-2 and consider our current understanding of the mechanisms of antibody-mediated neutralization in vitro, the antiviral mechanisms of nAbs that become relevant if effector cells are included in typical in vitro assays and the mechanisms of nAb activity against viruses in vivo

Progress on priming HIV-1 immunity