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Description
His-G6PD (1.1 g) and His-GSTP1 protein (1.1 g) were incubated with GST-SRC beads in the reaction buffer (20 mM HEPES, pH 7.5, 100 mM NaCl) overnight with or without 20 mM lactic acid, washed for four times and analyzed by Western Blotting, which were stained by Coomassie Brilliant Blue
This finding is highly consistent with clinical manifestations of PLS patients, supporting the conclusion that DPP1 inhibition has limited impact on host defense functions at therapeutic doses
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Folia Biologica (Praha)
