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425,426,427,428 Targeting the Keap1/PGAM5/AIFM1 axis in ROS-mediated oxieptosis could selectively amplify oxidative stress to induce programmed cell death in cancer cells, offering a novel therapeutic strategy

Glutathione is your body's primary intracellular antioxidant, central to liver detoxification pathways
There-after, due to an endosymbiotic association that the prokaryotes established with primitive eukaryotes after their internalization, they evolved into mitochondria

(1)] was first identified 90 years ago by Butz and du Vigneaud during their investigation of decomposition products of methionine (2, 3)