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Typically, -synuclein localizes to the mitochondria-associated membrane, and its presence may disrupt mitochondrial function by promoting the formation of the mitochondrial permeability transition pore (mPTP), leading to mitochondrial membrane potential (MMP) loss, subsequent mitochondrial degradation, and ultimately cell death (192)

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Maruta T, Tanouchi A, Tamoi M, Yabuta Y, Yoshimura K, Ishikawa T, Shigeoka S (2010) Arabidopsis chloroplastic ascorbate peroxidase isoenzymes play a dual role in photoprotection and gene regulation under photooxidative stress

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