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Nationwide Trends in Pancreatitis and Pancreatic Cancer Risk Among Patients With Newly Diagnosed Type 2 Diabetes Receiving Dipeptidyl Peptidase 4 Inhibitors

On the other hand, l-carnitine, primarily sourced from red meat, is obtained exogenously through dietary intake 28 .Dietary l-carnitine is metabolized in humans in a gut microbiota-dependent manner to form -butyrobetaine (GBB), which is subsequently converted into trimethylamine (TMA), a precursor of trimethylamine N-oxide (TMAO) 29

Since it has been observed that urinary MMA excretion decreased even more significantly after KT or combined liver/kidney transplantation than after single LT, it has been suggested that KT not only corrects renal dysfunction but may also be sufficient to ensure partial correction of methylmalonyl-CoA mutase activity to prevent metabolic decompensation

[DOI] [PubMed] [Google Scholar] 29.Wang S., Han C., Lee S.J., Patkar A.A., Masand P.S., Pae C.H