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Where the repeatability of a measurement series matters, a ready solution of known concentration reduces preparation error relative to a vial reconstituted separately at each use

A.RaboudJ.CotterchioM.StrohmaierS.WillettW.et al (2019)

As granulomas mature, they develop fibrous walls and experience a significant decrease in the number of vessels penetrating the structure, which hampers the penetration of anti-TB drugs into the necrotic and hypoxic areas of the granuloma, where M.tb persists [98, 99]
