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ASCT2 is substantially upregulated in PC tissues, mediates Gln uptake into PC cells [30] and promotes cell proliferation, migration, and invasion [31]

Therapeutic potential of targeting /-Hydrolase domain-containing 6 (ABHD6)

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Whilst XDHs in mammals can be converted into xanthine oxidases that produce both O 2 and H 2 O 2 , plant XDHs only form O 2 , which can be swiftly dismutated into H 2 O 2 ( 2 and H 2 O 2 at the apoplast ( 2 O 2 formation is favoured at high pH in the presence of reductants ( 2 O 2 ( For fruit tissues, however, knowledge is still lacking on the exact contribution of each source of ROS